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Nicolaas Arjan DE GROOT 27 Documents Identifiants chercheurs nicolaas-arjan-de-groot ResearcherId : AAY-1600-2021 0000-0003-2202-5279 IdRef : 151919712 ResearcherId : http://www.researcherid.com/rid/AAY-1600-2021 Présentation BIAM (CEA/CNRS/AMU) Publications Année de production Nom des revues Mots-clés Projets ANR Article dans une revue (25)
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Arjan de Groot
chercheur / scientist (molecular biology) CEA 2005 - aujourd'hui 19 ans AIO & PostDoc Utrecht University 1989 - 1999 10 ans Post Doc CNRS Marseille 1996 - 1998 2 ans Formation Rijksuniversiteit.
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Arjan De Groot Overview Bio Network 21 Publications 40 Editorial Contributions 1 Impact Present activities and research interests: Since 2004 I work at the CEA Cadarache (France), where I develop and supervise the project that aims at understanding the mechanisms underlying extreme radiation and desiccation tolerance in Deinococcus bacteria.
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Laurence Blanchard 1 , Arjan de Groot 1 Affiliation 1Molecular and Environmental Microbiology Team, Aix Marseille Univ, CEA, CNRS, BIAM, F-13108 Saint Paul-Lez-Durance, France. PMID: 33923690 PMCID: PMC8072749 DOI: 10.3390/cells10040924 Abstract
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Arjan de Groot, David Roche, Bernard Fernandez, Monika Ludanyi, Stéphane Cruveiller, David Pignol, David Vallenet, Jean Armengaud, Laurence Blanchard, RNA Sequencing and Proteogenomics Reveal the Importance of Leaderless mRNAs in the Radiation-Tolerant Bacterium Deinococcus deserti, Genome Biology and Evolution, Volume 6, Issue 4, April 2014.
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PMCID: PMC6300522 DOI: 10.1093/femsre/fuy037 Abstract Deinococcus bacteria are famous for their extreme resistance to ionising radiation and other DNA damage- and oxidative stress-generating agents. More than a hundred genes have been reported to contribute to resistance to radiation, desiccation and/or oxidative stress in Deinococcus radiodurans.
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On the basis of our RNA-seq and proteogenomics data, we propose that translation of many of the novel leaderless transcripts, which may have resulted from single-nucleotide changes and maintained by selective pressure, provides a new explanation for the generation of a cellular pool of small peptides important for protection of proteins against.
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